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Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer's and Parkinson's diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson's disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.
- Sales Rank: #3502286 in Books
- Published on: 2005-07-11
- Ingredients: Example Ingredients
- Original language: English
- Number of items: 1
- Dimensions: 10.87" h x 2.01" w x 8.62" l, 6.90 pounds
- Binding: Hardcover
- 1008 pages
Review
"Research in this area is a moving target, difficult to capture in a book, but Beal and colleagues have made a worthy effort...a weighty and comprehensive overview with an all-star list of contributors."
Kenneth Fischbeck, New England Journal of Medicine
"Neurodegenerative Diseases is one of the most comprehensive books to appear on the subject in the past decade...discusses all the neurodegenerative illnesses, with special attention to biological, pathophysiological, clinical, and therapeutic aspects, rather than focusing on a single facet...a comprehensive, well-written textbook. It is an excellent reference to have and return to again and again as an authoritative source on neurodegeneration."
Journal of the American Medical Association
"...there is a large amount of information, which will repay careful reading, perhaps especially for those new to the field. The book has high production values. A highly desirable addition for the departmental library."
Advances in Clinical Neuroscience and Rehabilitation, AJ Larner
"This encyclopedic book is a presentation of the totality of neurodegenerative disorders in the form of 62 highly readable essays from more than 100 distinguished contributors. The editors have succeeded with their intent of making this the most authoritative reference source for both clinicians and neuroscientists interested in these important clinical problems. The essays are organized in a coherent and seamless fashion, with every aspect of neurodegeneration considered... every recognized degenerative process of the central nervous system is discussed. The organization of the book is systematic. This resource should be available to any clinician dealing with neurodegenerative disorders or any scientist investigating neurodegeneration. I recommend the book highly and believe it will prove an invaluable resource for individuals interested in this important and devastating group of human illnesses. The price is appropriate and the title is a precise reflection of the contents."
Journal of Neurosurgery
About the Author
Flint Beal is Anne Parrish Titzell Professor and Chairman of the Department of Neurology and Neuroscience at the Weill Medical College of Cornell University, and Director of Neurology at the New York Presbyterian Cornell Campus. An internationally recognized authority on neurodegenerative disorders, his research has focused on the mechanism of neuronal degeneration in Alzheimer's disease, Huntington's disease, Parkinson's disease and amyotrophic lateral sclerosis.
Anthony Lang is Professor in the Department of Medicine, Division of Neurology, University of Toronto. A founding member of the Parkinson Study Group and the Movement Disorders Society, his research has included clinical trials of poorly recognized neurological disorders, clinical trials of new therapeutic modalities, and studies in molecular biology, neurophysiology, neuropsychology and imaging.
Albert Ludolph is Professor of Neurology, Chair of Neurology, and Chairman of the Neuroscience Center of the University of Ulm, Germany. A neurologist and psychiatrist, his major interest is in toxicological models of vulnerability and genetic models for the pathogenesis of neurodegenerative diseases.
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