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This introductory textbook explores bacterial disease mechanisms and bacteria-host interactions. The central premise is that bacteria have evolved by means of manipulating normal host cell functions and overcoming host defense systems to ensure their survival. As well as offering a new perspective on the classical bacterial virulence mechanisms, this book outlines the new molecular techniques developed to unravel the complexity of bacteria-host interactions. Current research may lead not only to a better understanding of disease mechanisms, but also to new means of preventing and/or treating bacterial infections.
- Sales Rank: #2577728 in Books
- Brand: Cambridge University Press
- Published on: 2002-05-13
- Ingredients: Example Ingredients
- Original language: English
- Number of items: 1
- Dimensions: 9.69" h x 1.38" w x 7.44" l, 2.68 pounds
- Binding: Paperback
- 692 pages
- Used Book in Good Condition
Review
"...the authors provide a comprehensive introduction to this exciting hybrid of disciplines..." ASM News
"...a welcome teaching tool for introducing students to this rapidly growing field.... this text offers a comprehensive look at the molecular mechanisms that allow bacterial pathogens to manipulate normal host cell functions for their own benefit.... the authors do an impressive job of providing an up-to-date view of the major concepts in the interactions between prokaryotic pathogens and their eukaryotic hosts.... Bacterial Disease Mechanisms is likely to become a mainstay for those who teach microbial pathogenesis as well as a useful starting point for researchers interested in acquainting themselves with concepts underpinning this exciting field." Cell become a mainstay..." Cell
About the Author
Michael Wilson is currently Professor of Microbiology in the Faculty of Clinical Sciences, University College London, and Head of the Department of Microbiology at the Eastman Dental Institute, University College London. He is the co-editor of Community Structure and Co-operation in Biofilms, 2000 (0521793025) and editor of Bacterial Adhesion to Host Tissues, 2001 (0521801079). His main research interests are bacterial virulence factors, biofilms and the development of new antimicrobial strategies.
Brian Henderson is Professor of Cell Biology and Head of the Cellular Microbiology Research Group at the Eastman Dental Institute, University College London. His research centres around cytokine biology and the interactions of bacteria with myeloid and lymphoid cells.
Rod McNab is Lecturer in Molecular Microbiology at the Eastman Dental Institute, University College London, and works on streptococcal adhesion and colonization factors, biofilms and bacterial cell-cell communication.
Most helpful customer reviews
1 of 1 people found the following review helpful.
Old but gold
By Dilip K. Challa
This book is old but you will enjoy every explaination in this book. I would say this is one of the most interesting bacterial mechanism book you can find. I especially love the order of content in this book. Buy this if you want to know the basic mechanism behind a toxin's effect or how a bacteria attaches to its host cell.
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